What is Pseudoephedrine?
Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, like treatment of low blood pressure. At higher doses, it may produce various additional effects, including psychostimulant, appetite suppressant, and performance-enhancing effects. In relation to this, non-medical use of pseudoephedrine has been encountered. The medication is taken by mouth.
Pseudoephedrine Side effects
Side effects of pseudoephedrine include insomnia, increased heart rate, and increased blood pressure, among others. Rarely, pseudoephedrine has been associated with serious cardiovascular complications like heart attack and hemorrhagic stroke. Some people may be more sensitive to its cardiovascular effects. Pseudoephedrine acts as a norepinephrine releasing agent, thereby indirectly activating adrenergic receptors. As such, it is an indirectly acting sympathomimetic. Pseudoephedrine significantly crosses into the brain, but has some peripheral selectivity due to its hydrophilicity. Chemically, pseudoephedrine is a substituted amphetamine and is closely related to ephedrine, phenylpropanolamine, and amphetamine. It is the (1S,2S)-enantiomer of β-hydroxy-N-methylamphetamine.
Sudafed (Pseudoephedrine) Legal status
The regulation of therapeutic goods, defined as drugs and therapeutic devices, varies by jurisdiction. In some countries, such as the United States, they are regulated at the national level by a single agency. In other jurisdictions they are regulated at the state level, or at both state and national levels by various bodies, as in Australia.
Uses
- Provides 12-hour relief of nasal congestion due to the common cold, hay fever or other upper respiratory allergies
- Temporarily relieves sinus congestion and pressure
Active Ingredients:
Pseudoephedrine HCl 120 mg – Nasal decongestant
Inactive Ingredients:
Candelilla wax, FD&C blue no. 1 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, olyethylene glycol, povidone, propylene glycol, shellac, talc, titanium dioxide
Adults and children 12 years and over:
- Take 1 tablet every 12 hours
- Do not take more than 2 caplets in 24 hours
Children under 12 years:
- Do not use this product in children under 12 years of age
Do not use if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if you have
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- trouble urinating due to an enlarged prostate gland
When using this product do not exceed recommended dosage
Stop use and ask a doctor if
- nervousness, dizziness, or sleeplessness occur
- symptoms do not improve within 7 days or occur with a fever
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
- Store at 20-25⁰C (68-77⁰F) in dry place
- Each tablet contains: calcium 45 mg
- Protect from light
Questions or comments?
Call 1-888-217-2117 (toll-free) or 215-273-2755 (collect)
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